Realizamos entrevistas cualitativas con 28 YB-GBMSM que viven con el VIH para explorar las manifestaciones de homonegatividad a lo largo del curso de la vida. La teoría del estrés de las minorías postula que la homonegatividad, ya sea experimentada, anticipada o internalizada, afecta negativamente a la salud. Future interventions should work with youth, families, and churches to prevent these harmful experiences. In conclusion, experienced, anticipated and internalized homonegativity were pervasive as YB-GBMSM navigated family and religious environments over the life course. Most participants eventually reached self-acceptance of both their sexuality and HIV status. Ultimately, many participants distanced themselves from home environments, seeking and often finding extrafamilial support. These experiences led to anticipated and internalized homonegativity, which in turn shaped sexual identity formation processes in adolescence and into young adulthood. Stifling, and sometimes traumatic, familial and religious environments led to experienced homonegativity early in life. Thematic analysis identified patterns in the ways that homonegativity was discussed at different points in participants’ lives. We conducted qualitative interviews with 28 YB-GBMSM living with HIV to explore manifestations of homonegativity over the life course. Minority stress theory posits that homonegativity – whether experienced, anticipated, or internalized – adversely impacts health.